Durability of lopinavir/r monotherapy in people with viral load ≤50 copies/Ml
نویسندگان
چکیده
منابع مشابه
Durability of lopinavir/ritonavir monotherapy in individuals with viral load ≤50 copies/ml in an observational setting.
BACKGROUND The main objective is to evaluate the efficacy and durability of lopinavir-ritonavir monotherapy (LPV/r-MT) in virologically controlled HIV-positive individuals switching from combination antiretroviral therapy (cART). METHODS Criteria to be included in this observational study were to have initiated for the first time LPV/r-MT after ≥2 consecutive HIV RNA≤50 copies/ml achieved on ...
متن کاملDurability of lopinavir/ritonavir dual-therapies in individuals with viral load <50 copies/mL in the observational setting
INTRODUCTION We aimed at evaluating the efficacy and durability of a lopinavir/ritonavir-based dual regimen (LPV/r-DR) in virologically controlled HIV-infected individuals in current clinical practice. METHODS Patients who have initiated for the first time a LPV/r-DR with HIV-RNA<50 copies/mL were included in this observational study. The main endpoints were: time to virological rebound [VR=t...
متن کاملAssessment of HTLV-I proviral load, HIV viral load and CD4 T cell count in infected subjects; with an emphasis on viral replication in co-infection
Objective(s): HTLV-I and HIV virus quantification is an important marker for assessment of virus activities. Since there is a direct relationship between the number of virus and disease progression, HTLV- I and HIV co-infection might have an influence on the development of viral associated diseases, thus, viral replication of these viruses and co-infection were evaluated. Materials and...
متن کاملChanging antiretrovirals whilst viral load <50 copies/ml and relationship with CD4 count changes
Methods 6713 patients from EuroSIDA on cART with a confirmed VL<50 copies/ml were included; a regimen change was defined as >1 ARV change (occurring on the same day) for any reason whilst VL< 50 copies/ml. Baseline was defined as the first VL<50 copies/ml on cART; Kaplan Meier methods estimated the probability of ARV change and Cox proportional hazards models, stratified by centre, identified f...
متن کاملGlycemic durability of rosiglitazone, metformin, or glyburide monotherapy.
BACKGROUND The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term glycemic control in type 2 diabetes is not known. METHODS We evaluated rosiglitazone, metformin, and glyburide as initial treatment for recently diagnosed type 2 diabetes in a double-blind, randomized, controlled clinical trial involving 4360 patients. The patients...
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ژورنال
عنوان ژورنال: Journal of the International AIDS Society
سال: 2012
ISSN: 1758-2652
DOI: 10.7448/ias.15.6.18378